Patterns of gene expression are to organisms as melodies and harmonies are to sonatas. It's all about which sets of proteins appear in a cell at the same time (the chords) and which sets come before or after other sets (the themes) and at what rate they appear (the tempos) and how they modulate one another (the developments and transitions). When these patterns go awry we may see malignancy. When they change by mutation we can get new kinds of organisms. When they work, we get a creature.
Ursula GoodenoughRelated topics
appear change mutation see work geneRelated quotes
In science it often happens that scientists say, 'You know that's a really good argument; my position is mistaken,' and then they would actually change their minds and you never hear that old view from them again. They really do it. It doesn't happen as often as it should, because scientists are human and change is sometimes painful. But it happens every day. I cannot recall the last time someting like that happened in politics or religion.
Carl Sagan
In asking forgiveness of women for our mythologizing of their bodies, for being unreal about them, we can only appeal to their own sexuality, which is different but not basically different, perhaps, from our own. For women, too, there seems to be that tangle of supplication and possessiveness, that descent toward infantile undifferentiation, that omnipotent helplessness, that merger with the cosmic mother-warmth, that flushed pulse-quickened leap into overestimation, projection, general mix-up.
John Updike
Of the various executive abilities, no one excited more anxious concern than that of placing the interests of our fellow-citizens in the hands of honest men, with understanding sufficient for their stations. No duty is at the same time more difficult to fulfil. The knowledge of character possessed by a single individual is of necessity limited. To seek out the best through the whole Union, we must resort to the information which from the best of men, acting disinterestedly and with the purest motives, is sometimes incorrect.
Thomas Jefferson
Now a writer can make himself a nice career while he is alive by espousing a political cause, working for it, making a profession of believing in it, and if it wins he will be very well placed. All politics is a matter of working hard without reward, or with a living wage for a time, in the hope of booty later. A man can be a Fascist or a Communist and if his outfit gets in he can get to be an ambassador or have a million copies of his books printed by the Government or any of the other rewards the boys dream about.
Ernest Hemingway
The nude gains its enduring value from the fact that it reconciles several contrary states. It takes the most sensual and immediately interesting object, the human body, and puts it out of reach of time and desire; it takes the most purely rational concept of which mankind is capable, mathematical order, and makes it a delight to the senses; and it takes the vague fears of the unknown and sweetens them by showing that the gods are like men and may be worshiped for their life-giving beauty rather than their death-dealing powers.
Kenneth Clark