Part of the charm of synthetic organic chemistry derives from the vastness of the intellectual landscape along several dimensions. First, there is the almost infinite variety and number of possible target structures that lurk in the darkness waiting to be made. Then, there is the vast body of organic reactions that serve to transform one substance into another, now so large in number as to be beyond credibility to a non-chemist. There is the staggering range of reagents, reaction conditions, catalysts, elements, and techniques that must be mobilized in order to tame these reactions for synthetic purposes. Finally, it seems that new information is being added to that landscape at a rate that exceeds the ability of a normal person to keep up with it. In such a troubled setting any author, or group of authors, must be regarded as heroic if through their efforts, the task of the synthetic chemist is eased.
Elias James CoreyRelated topics
ability almost beyond body chemistry credibility darkness heroic intellectual large now number order organic person possible reaction serve staggering synthetic task transform vast vastness waitingRelated quotes
A number of proposals have been advanced in recent years for the development of ‘general systems theory' which, abstracting from properties peculiar to physical, biological, or social systems, would be applicable to all of them. We might well feel that, while the goal is laudable, systems of such diverse kinds could hardly be expected to have any nontrivial properties in common. Metaphor and analogy can be helpful, or they can be misleading. All depends on whether the similarities the metaphor captures are significant or superficial.
It may not be entirely vain, however, to search for common properties among diverse kinds of complex systems... The ideas of feedback and information provide a frame of reference for viewing a wide range of situations, just as do the ideas of evolution, of relativism, of axiomatic method, and of operationalism... hierarchic systems have some common properties that are independent of their specific content...
Herbert Simon
Harry Dresden: There's power in the night. There's terror in the darkness. Despite all our accumulated history, learning, and experience, we remember. We remember times when we were too small to reach the light switch on the wall, and when the darkness itself was enough to make us cry out in fear. Get a good ways out from civilization-say, miles and miles away on a lightless lake-and the darkness is there, waiting. Twilight means more than just time to call the children in from playing outside. Fading light means more than just the end of another day. Night is when terrible things emerge from their sleep and seek soft flesh and hot blood. Night is when unseen beings with no regard for what our people have built and no place in what we have deemed the natural order look in at our world from outside, and think dark and alien thoughts. And sometimes, just sometimes, they do things.
Jim Butcher
The shattering of modern culture is the result, on the plane of ideological struggle, of the chaotic crisis of these antagonisms. The new desires that are taking shape are presented in distorted form: present-day resources could enable them to be fulfilled, but the anachronistic economic structure is incapable of developing these resources to such ends. Ruling-class ideology has meanwhile lost all coherence because of the depreciation of its successive conceptions of the world (a depreciation which leads the ruling class to historical indecision and uncertainty); because of the coexistence of a range of mutually contradictory reactionary ideologies (such as Christianity and social-democracy); and because of the mixing into contemporary Western culture of a number of only recently appreciated features of several foreign civilizations. The main goal of ruling-class ideology is therefore to maintain this confusion.
Guy Debord
In the development of any science, the first received paradigm is usually felt to account quite successfully for most of the observations and experiments easily accessible to that science's practitioners. Further development, therefore, ordinarily calls for the construction of elaborate equipment, the development of an esoteric vocabulary and skills, and a refinement of concepts that increasingly lessens their resemblance to their usual common-sense prototypes. That professionalization leads, on the one hand, to an immense restriction of the scientist's vision and to a considerable resistance to paradigm change. The science has become increasingly rigid. On the other hand, within those areas to which the paradigm directs the attention of the group, normal science leads to a detail of information and to a precision of the observation-theory match that could be achieved in no other way.
Thomas Samuel Kuhn
Microeconomics, including the study of individual choice and of group choice in market and nonmarket processes, has generally been considered a field science as distinct from an experimental science. Hence microeconomics has sometimes been classified as "non-experimental" and closer methodologically to meteorology and astronomy than to physics and experimental psychology (Marschak, 1950, p. 3; Samuelson, 1973, p. 7). But the question of using experimental or nonexperimental techniques is largely a matter of cost, and generally the cost of conducting the most ambitious and informative experiments in astronomy, meteorology, and economics varies from prohibitive down to considerable. The cost of experimenting with different solar system planetary arrangements, different atmospheric conditions, and different national unemployment rates, each under suitable controls, must be regarded as prohibitive.
Vernon L. Smith