We do not inhabit a perfected world where natural selection ruthlessly scrutinizes all organic structures and then molds them for optimal utility. Organisms inherit a body form and a style of embryonic development; these impose constraints upon future change and adaptation. In many cases, evolutionary pathways reflect inherited patterns more than current environmental demands. These inheritances constrain, but they also provide opportunity. A potentially minor genetic change [...] entails a host of complex, nonadaptive consequences. [...] What "play” would evolution have if each structure were built for a restricted purpose and could be used for nothing else? How could humans learn to write if our brain had not evolved for hunting, social cohesion, or whatever, and could not transcend the adaptive boundaries of its original purpose?
 
    
        Stephen Jay Gould 
     
    
     
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        We have entered a time of global transition marked by uniquely contradictory trends. Regional and continental associations of States are evolving ways to deepen cooperation and ease some of the contentious characteristics of sovereign and nationalistic rivalries. National boundaries are blurred by advanced communications and global commerce, and by the decisions of States to yield some sovereign prerogatives to larger, common political associations. At the same time, however, fierce new assertions of nationalism and sovereignty spring up, and the cohesion of States is threatened by brutal ethnic, religious, social, cultural or linguistic strife. Social peace is challenged on the one hand by new assertions of discrimination and exclusion and, on the other, by acts of terrorism seeking to undermine evolution and change through democratic means. 
         
 
    Boutros Boutros-Ghali 
 
                 
            
        
     
    
    
    
    
    
    
                                        
                    
    
        The need for a fundamentally different approach to the study of physical processes at the molecular level motivated the development of relevant statistical methods, which turned out to be applicable not only to the study of molecular processes (statistical mechanics), but to a host of other areas such as the actuarial profession, design of large telephone exchanges, and the like. In statistical methods, specific manifestations of microscopic entities (molecules, individual telephone sites, etc.) are replaced with their statistical averages, which are connected with appropriate macroscopic variables. The role played in Newtonian mechanics by the calculus, which involves no uncertainty, is replaced in statistical mechanics by probability theory, a theory whose very purpose is to capture uncertainty of a certain type. 
         
 
    George Klir 
 
                 
            
        
     
    
    
                                        
                    
    
        I gave up on this stuff. I gave up on my species and ... I gave up on my countrymen. Because I think we squandered great gifts. I think humans were given great great gifts: walking upright, binocular vision, opposable thumb, large brain ... We grew. We had great gifts, and we gave it all up for both money and God ... We gave it all up to superstition, primitive superstition, primitive shit ... Invisible man in the sky, looking down, keeping track of what we do, make sure we don't do the wrong thing, if we do, he puts us in hell, where we burn forever. That kind of shit is very limiting for this brain we have. So we keep ourselves limited. And then we want a toy and a gizmo and gold and we want shiny things, and we want something to plug in that will make big big big things for us... And all that shit is nothing! It's nothing. 
         
 
    George Carlin